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Istovremena primena leka Bensedin i opioida (lekova za ublažavanje jakih bolova, lekova za supstitucionu terapiji i određenih lekova protiv kašlja) povećava rizik od pospanosti, otežanog disanja (respiratorna depresija), kome što sve može biti životno ugrožavajuće. Zbog toga istovremenu primenu treba razmotriti samo ukoliko druge terapijs
Extended-release sorts of tramadol could possibly be Utilized in Grown ups who involve around-the-clock therapy in their ache for an extended period.tell your medical doctor In case you have any on the situations pointed out inside the IMPORTANT WARNING segment, a blockage or narrowing of the stomach or intestines, or paralytic ileus (affliction in
The concomitant utilization of tramadol hydrochloride and CYP2D6 inhibitors could lead to a rise in the plasma concentration of tramadol along with a lower while in the plasma focus of M1, particularly when an inhibitor is additional following a secure dose of tramadol hydrochloride is obtained. Considering the fact that M1 is a more strong μ-opio